ANTIVIRAL PROPERTIES OF THE NATURAL POLYPHENOLS DELPHINIDIN AND EPIGALLOCATECHIN GALLATE AGAINST THE FLAVIVIRUSES WEST NILE VIRUS, ZIKA VIRUS, AND DENGUE VIRUS

The Flavivirus genus contains important pathogens, such as West Nile virus (WNV), Zika virus (ZIKV), and Dengue virus (DENV), which are enveloped plus-strand RNA viruses transmitted by mosquitoes and constitute a worrisome threat to global human and animal health.Currently no licensed drugs against them are available, being, thus, still necessary t

There are many different mathematical models that can be used to describe Cassette relations between energy machines in the power-split hybrid drive system.Usually, they are created based on simulations or measurements in bench (laboratory) conditions.In that sense, however, these are the idealized conditions.It is not known how the internal combus

Chronic hepatitis B virus (HBV) infection, which ultimately leads to liver cirrhosis, hepatic decompensation, and hepatocellular carcinoma (HCC), remains a significant disease burden worldwide.Despite the use of antiviral therapy (AVT) using oral nucleos(t)ide analogs (NUCs) with high genetic barriers, the risk of HCC development cannot be complete